Stevia, sucralose and sucrose added to a maqui-Citrus beverage and their effects on glycemic response in overweight subjects: A randomized clinical trial

Background: Low-caloric sweeteners represent a good alternative to the extra boost of energy sugar-sweetened beverages. However, their long-term effects have barely been assessed. In present study, influence low-caloric added maqui/Citrus beverage on glycemic profile has evaluated. Methods: A parallel, randomized and triple blind clinical study was performed in overweight subjects (n = 138), who consumed 330 mL/day with Stevia, Sucralose or Sucrose, for 60 days. Results: BMI did not change significantly any treatment. Fasting glucose increased after short-term consumption Sucrose (26%), as well addition sweeteners, but lesser extent: 11% Stevia 20% Sucralose. Insulin concentrations drink, which resulted significant increase HOMA-IR (p 0.002) 0.001). Conclusions: The results obtained link sucrose sweetened beverages disbalance glycaemic response, better response addition, although it also produces certain negative control. evidence available date is conclusive enough advise wide use LCS. ClinicalTrials.gov NCT 04016337.